diff --git a/components/openthread/src/esp_openthread_platform.cpp b/components/openthread/src/esp_openthread_platform.cpp
index 3e73ef362a..8beb8143dc 100644
--- a/components/openthread/src/esp_openthread_platform.cpp
+++ b/components/openthread/src/esp_openthread_platform.cpp
@@ -94,14 +94,18 @@ static esp_err_t esp_openthread_host_interface_init(const esp_openthread_platfor
 {
     esp_openthread_host_connection_mode_t host_mode = get_host_connection_mode();
     switch (host_mode) {
+#if CONFIG_OPENTHREAD_RCP_SPI
     case HOST_CONNECTION_MODE_RCP_SPI:
         ESP_RETURN_ON_ERROR(esp_openthread_host_rcp_spi_init(config), OT_PLAT_LOG_TAG,
                           "esp_openthread_host_rcp_spi_init failed");
         break;
+#endif
+#if CONFIG_OPENTHREAD_RCP_UART
     case HOST_CONNECTION_MODE_RCP_UART:
         ESP_RETURN_ON_ERROR(esp_openthread_host_rcp_uart_init(config), OT_PLAT_LOG_TAG,
                           "esp_openthread_host_rcp_uart_init failed");
         break;
+#endif
 #if CONFIG_OPENTHREAD_CONSOLE_TYPE_UART
     case HOST_CONNECTION_MODE_CLI_UART:
         ESP_RETURN_ON_ERROR(esp_openthread_host_cli_uart_init(config), OT_PLAT_LOG_TAG,
diff --git a/components/openthread/src/port/esp_openthread_spi_slave.c b/components/openthread/src/port/esp_openthread_spi_slave.c
index 979e6067e7..754300e5c9 100644
--- a/components/openthread/src/port/esp_openthread_spi_slave.c
+++ b/components/openthread/src/port/esp_openthread_spi_slave.c
@@ -25,7 +25,6 @@
 #include <string.h>
 #include "driver/gpio.h"
 #include "driver/spi_slave.h"
-#include "esp_private/cache_utils.h"
 #include "esp_private/spi_slave_internal.h"
 #include "ncp/ncp_config.h"
 #include "openthread/error.h"